About Genome Comparator

Genome Comparator is used to compare whole genome data of isolates within a database using either the database defined loci (regions) or the coding sequences of an annotated genome as the comparator.

Here, we implement Genome Comparator to allow users to compare genomes across curated collections of genomic data hosted on our platform.

Why is it useful?

UNDER REVIEW ⚠️

Genome Comparator helps researchers identify similarities and differences between genomes to understand genetic relationships, track evolutionary changes, and identify potential functional differences.

Some use cases include ...

How to use it?

STEP 1 Go to the collections page to select the organism's database you want to search against.

Selecting a collection to search against.

STEP 2 Log in using your PubMLST credentials.

Logging in button highlighted in red on the overview page of selected collection.
Main collection login page. Use PubMLST credentials.
Overview page of selected collection after logging in.

STEP 3 To access the tool's page, either click on the Analysis tab to display a link or find a button to the plugin at the bottom of a search results.

Accessing 'Genome Comparator' tool via Analysis tab.
Accessing 'Genome Comparator' tool via button at the bottom of search results.

STEP 4 Once you see the Genome Comparator interface, choose the comparator scheme (database loci or annotated genome CDS), upload/select isolates, configure thresholds, and run the comparison.

UNDER REVIEW ⚠️
Genome Comparator interface where users configure comparison parameters.

Where to find out more?

Genome Comparator is implementated as part of BIGSdb, the software powering PubMLST.

There is more detailed information about Genome Comparator and its different parameters here.

Contact us

For queries and to report any issues, email us at: email[at]biology.ox.ac.uk

Ineos Oxford Institute for antimicrobial research

University of Oxford

Sir William Dunn School of Pathology

South Parks Road

Oxford, OX1 3RE

United Kingdom

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